Side effects after the administration of haloperidol decanoate the same, which may occur when using other forms of haloperidol. Extrapyramidal symptoms Prolonged nandrolone phenylpropionate use may occur tremor, muscle rigidity, bradykinesia, akathisia, acute muscular dystonia, oculogyric crisis, laryngeal dystonia (spasmodic dysphonia). Correction: should be given anti-Parkinsonian drugs are anticholinergic action. However, it should be understood that their use reduces the constant efficiency haloperidol. Tardive dyskinesia As with other antipsychotic drugs, can occur with prolonged use or withdrawal of the drug. Manifested rhythmic, not susceptible to volitional control facial movements, muscle area, lips, tongue or jaw.
This disorder in some patients may be in the nature of residual effects. Disorders terminated when resuming use of haloperidol, while increasing the dose or switching to another drug treatment. If signs of tardive dyskinesia it is advisable to continue treatment with another drug. Neuroleptic malignant syndrome The use of haloperidol may cause CSN. Rare reactions that occur on the type of idiosyncrasy, characterized by hyperthermia, generalized muscle rigidity, autonomic lability, difficult or rapid breathing, arrhythmia, increased or decreased blood pressure (BP), increased sweating, urinary incontinence, seizures, and a violation of the patient’s consciousness. An early sign of NSA is often hyperthermia. If you have symptoms of in all cases it is necessary to interrupt treatment with antipsychotics and, under careful observation, began to support, including detoxication, therapy. Other side effects of CNSdepression, lethargy (up to the state, like lethargy) or psychomotor agitation, insomnia or sleepiness (especially at the beginning of treatment), headache, transient mnestiko-intellectual disturbances, dizziness, restlessness, anxiety, fear, or euphoria, seizures such as “grand mal” and the resumption of psychotic symptoms (development of paradoxical reactions). Digestive system When used in high doses -. loss of appetite, dry mouth, sialoschesis, nausea, vomiting, diarrhea or constipation, abnormal liver function, until the development of jaundice Endocrine system due antidofaminovogo actions may occur hyperprolactinemia, galactorrhea, gynecomastia, oligo- and amenorrhea. Rarely – hyper or hypoglycemia, and decreased secretion of antidiuretic hormone. Cardiovascular system when used in high doses – decreased blood pressure, orthostatic hypotension, arrhythmia, tachycardia, changes in the electrocardiogram (prolongation of QT interval). From the side of hematopoiesis rare – temporary leukopenia or leukocytosis, agranulocytosis, erythropenia and tendency to monocytosis, Allergic reactions such as the phenomenon of urticaria, anaphylaxis, photosensitivity, maculopapular and akneobraznye skin changes, rarely -. bronchospasm, laryngospasm, hyperpyrexia with the genitourinary system urinary retention (for benign prostatic hyperplasia) , peripheral edema, decreased potency, increase libido, priapism. Laboratory tests hyponatremia. Other side effects of alopecia, heat stroke, weight gain, local reactions, cataracts, retinopathy, blurred vision. Elderly patients may experience bouts of angle-closure glaucoma.
Overdose (intoxication) . Symptoms nandrolone phenylpropionate of overdose of haloperidol decanoate are similar to those observed in the application of other forms of haloperidol.
If you suspect overdosing haloperidol decanoate should be considered long-acting nature of the drug.
The most important signs of overdose: severe extrapyramidal disorders (muscle stiffness, possible and muscular hypertonicity, general or localized tremor), arterial hypo- – sometimes hypertension, a condition marked inhibition. . In extreme cases, the possible onset of coma, respiratory depression with on the background of severe arterial hypotension
is necessary to consider the possibility of developing ventricular arrhythmias with prolongation. Treatment of overdose : No specific antidote. Symptomatic therapy: With a comatose state needs the support function of the respiratory system, if necessary, the connection to a respirator. Requiresnandrolone phenylpropionatemonitoring and other vital body functions. For the treatment of severe hypotension or circulatory failure must be intravenous sufficient volume of liquid, plasma, or concentrated albumin, as well as the appointment of vasopressor agents (noradrenaline and dopamine). Epinephrine in these cases use is strictly prohibited! In combination with haloperidol, it can cause severe arterial hypotension). In severe extrapyramidal symptoms should be used parenterally antiparkinsonian funds and central holinoblokatory.hemodialysis – is ineffective. terry crews steroids